Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.73 |
| ▸ | CA1 | P00915 | 6/20 | 0.73 |
| ▸ | CA2 | P00918 | 6/20 | 0.73 |
| ▸ | CA9 | Q16790 | 6/20 | 0.73 |
| ▸ | PTPRF | P10586 | 2/20 | 0.63 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | IDE | P14735 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3620407 | 1.00 | CA12 (0.73) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL6036966 | 1.00 | CA12 (0.73) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL565442 | 0.99 | CA12 (0.72) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL14253654 | 0.90 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL25374435 | 0.90 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL565441 | 0.90 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL19940249 | 0.88 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL21524959 | 0.88 | CA12 (0.78) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL18329586 | 0.88 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL12059002 | 0.88 | CA12 (0.74) | CA12CA1CA2CA9PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204444-A9 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170016040-A1 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-19 | — | — | US | disclosed |