Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.78 |
| ▸ | CA1 | P00915 | 6/20 | 0.78 |
| ▸ | CA2 | P00918 | 6/20 | 0.78 |
| ▸ | CA9 | Q16790 | 6/20 | 0.78 |
| ▸ | PTPRF | P10586 | 2/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | IDE | P14735 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12059001 | 0.94 | CA12 (0.70) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL12059002 | 0.89 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL18329586 | 0.89 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL19940249 | 0.89 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL14253654 | 0.89 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL23625183 | 0.89 | CA12 (0.71) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL18326514 | 0.89 | CA12 (0.71) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL18391007 | 0.88 | CA12 (0.73) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL6036966 | 0.88 | CA12 (0.73) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL3620407 | 0.88 | CA12 (0.73) | CA12CA1CA2CA9PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2023-11-02 | — | — | US | disclosed |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-09-05 | — | — | US | disclosed |
| US-20220106356-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2022-04-07 | — | — | US | disclosed |
| US-11161873-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2021-11-02 | — | — | US | disclosed |
| US-20200390901-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONOTHIOLATES AND - PHOSPHONATES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2020-12-17 | — | — | US | disclosed |
| US-20190330264-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390901-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONOTHIOLATES AND - PHOSPHONATES | ACP1, PTMS, ALG1 | CA12 525/4885CA1 1340/4885CA2 3722/4885 |
| US-20220106356-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PFAS, PHOSPHO1, PNKP | CA12 1660/4885CA1 2646/4885CA2 4473/4885 |
| US-20190330264-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PHOSPHO1, PFAS, PNKP | CA12 1946/4885CA1 2842/4885CA2 4487/4885 |
| US-11161873-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | TST, PHOSPHO1, TMT1A | CA12 3011/4885CA1 3274/4885CA2 4421/4885 |
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PFAS, PHOSPHO1, PNKP | CA12 1660/4885CA1 2646/4885CA2 4473/4885 |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | PFAS, PHOSPHO1, PNKP | CA12 1660/4885CA1 2646/4885CA2 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.