SCHEMBL3620407

SCHEMBL3620407

O=C(CCCCC1SC[C@@H]2NC(=O)N[C@H]12)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.73
CA1 P00915 6/20 0.73
CA2 P00918 6/20 0.73
CA9 Q16790 6/20 0.73
PTPRF P10586 2/20 0.63
PTPN2 P17706 2/20 0.63
PTPN1 P18031 2/20 0.63
TDP1 Q9NUW8 5/20 0.62
PKM P14618 2/20 0.62
MEN1 O00255 1/20 0.62
ABL1 P00519 1/20 0.62
LMNA P02545 1/20 0.62
IDE P14735 1/20 0.62
MAPK1 P28482 1/20 0.62
KMT2A Q03164 1/20 0.62
RIN1 Q13671 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
SLC6A3 Q01959 2/20 0.57
ITGB1 P05556 1/20 0.53
ITGA4 P13612 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18391007 1.00 CA12 (0.73) CA12CA1CA2CA9PTPRF
SCHEMBL6036966 1.00 CA12 (0.73) CA12CA1CA2CA9PTPRF
SCHEMBL565442 0.99 CA12 (0.72) CA12CA1CA2CA9PTPRF
SCHEMBL14253654 0.90 CA12 (0.74) CA12CA1CA2CA9PTPRF
SCHEMBL25374435 0.90 CA12 (0.74) CA12CA1CA2CA9PTPRF
SCHEMBL565441 0.90 CA12 (0.74) CA12CA1CA2CA9PTPRF
SCHEMBL19940249 0.88 CA12 (0.74) CA12CA1CA2CA9PTPRF
SCHEMBL21524959 0.88 CA12 (0.78) CA12CA1CA2CA9PTPRF
SCHEMBL18329586 0.88 CA12 (0.74) CA12CA1CA2CA9PTPRF
SCHEMBL12059002 0.88 CA12 (0.74) CA12CA1CA2CA9PTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 EP disclosed
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 EP disclosed
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 US disclosed
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 US disclosed
EP-3391876-B1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2021-03-10 EP disclosed
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG INC (US) 2020-12-31 US disclosed
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG INC (US) 2020-12-31 US disclosed
US-10751418-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2020-08-25 US disclosed
US-10751418-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2020-08-25 US disclosed
US-20200261363-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2020-08-20 US disclosed
US-20100247625-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-09-30 US disclosed
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. 2010-05-27 US disclosed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US disclosed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US disclosed
EP-2089026-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE PROMOTION OF PHYSIOLOGICAL CARDIAC HYPERTROPHY Novartis AG (CH) 2009-08-19 EP disclosed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US disclosed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US disclosed
WO-2008070552-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE PROMOTION OF PHYSIOLOGICAL CARDIAC HYPERTROPHY NOVARTIS AG (CH) 2008-06-12 WO disclosed
WO-2008067527-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS NOVARTIS AG (CH) 2008-06-05 WO disclosed
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal SDG, INC. 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal HAVCR2, IFNAR1, MSR1 CA12 3516/4885CA1 4190/4885CA2 4446/4885
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC CA12 3441/4885CA1 2920/4885CA2 2092/4885
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL HAVCR2, IFNAR1, IFNG CA12 3345/4885CA1 4092/4885CA2 4346/4885
US-11517529-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 CA12 3452/4885CA1 2966/4885CA2 2040/4885
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 CA12 3452/4885CA1 2966/4885CA2 2040/4885
US-20090087479-A1 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 CA12 2422/4885CA1 2202/4885CA2 1569/4885
US-20200261363-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL INSR, IAPP, GPR119 CA12 2944/4885CA1 2697/4885CA2 3633/4885
US-10751418-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 CA12 3452/4885CA1 2966/4885CA2 2040/4885
US-20100247625-A1 Orally Bioavailable Lipid-Based Constructs FABP2, LIPC, FABP6 CA12 1226/4885CA1 2890/4885CA2 3952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.