Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8785708 | 0.98 | MAPT (0.53) | MAPTKDM4ERAB9ATDP1NPC1 | |
| SCHEMBL11666858 | 0.84 | PPARA (0.48) | MAPTKDM4ERAB9ATDP1NPC1 | |
| SCHEMBL8856987 | 0.84 | GABRP (0.42) | MAPTKDM4ETDP1GABRPGABRD | |
| SCHEMBL11523096 | 0.82 | ALDH1A1 (0.42) | MAPTKDM4ETDP1GABRPGABRD | |
| SCHEMBL8888227 | 0.81 | POLB (0.55) | MAPTKDM4ERAB9ATDP1NPC1 | |
| SCHEMBL10955222 | 0.80 | GABRP (0.41) | MAPTKDM4EPOLBGABRPGABRD | |
| SCHEMBL9309430 | 0.80 | KDM4C (0.43) | MAPTKDM4ETDP1GABRPGABRD | |
| SCHEMBL9141154 | 0.79 | MAPT (0.51) | MAPTKDM4ERAB9APOLBALDH1A1 | |
| SCHEMBL12998745 | 0.79 | TDP1 (0.69) | MAPTKDM4ERAB9ATDP1NPC1 | |
| SCHEMBL2922856 | 0.78 | ALDH1A1 (0.39) | MAPTKDM4ERAB9ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374791-A1 | Insecticidal 4-phenyl-1H pyrazoles | Bayer CropScience Aktiengesellschaft (DE) | 2011-10-12 | — | — | EP | disclosed |
| EP-2321262-A1 | INSECTICIDAL 4-PHENYL-1H-PYRAZOLES | Bayer CropScience AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010017902-A1 | INSECTICIDAL 4-PHENYL-1H-PYRAZOLES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-02-18 | — | — | WO | disclosed |
| EP-0438230-B1 | Indole-substituted five-membered heteroaromatic compounds | MERCK SHARP & DOHME (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-5317103-A | Migraine treatment | MERCK SHARP & DOHME LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |