Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404940 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP2C19LMNAMEN1 | |
| SCHEMBL1837603 | 0.91 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2CYP2C19LMNAHPGD | |
| SCHEMBL1841787 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP1A2CYP2C19LMNAHPGD | |
| SCHEMBL1835248 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP1A2CYP2C19LMNAHPGD | |
| SCHEMBL1836616 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP1A2CYP2C19LMNAHPGD | |
| SCHEMBL1838812 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP1A2CYP2C19LMNAHPGD | |
| SCHEMBL940109 | 0.87 | ALDH1A1 (0.62) | SMN1; SMN2CYP1A2CYP2C19LMNAMEN1 | |
| SCHEMBL28108900 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP2C19LMNAMEN1 | |
| SCHEMBL28335642 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2CYP2C19LMNAHPGD | |
| SCHEMBL8057144 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP1A2CYP2C19LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752405-B1 | METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYAMINO FORMATE | INST PROCESS ENG CAS (CN) | 2018-08-22 | — | — | EP | disclosed |
| EP-2322504-B9 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-2322504-B1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-9249090-B2 | N-substituted carbamic acid ester production method and isocyanate production method using the N-substituted carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-02-02 | — | — | US | disclosed |
| US-9062161-B2 | Method for preparing polymethylene polyphenyl polycarbamate | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2015-06-23 | — | — | US | disclosed |
| US-20150038742-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-02-05 | — | — | US | disclosed |
| US-8884047-B2 | N-substituted carbamic acid ester production method and isocyanate production method using the N-substituted carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20140316100-A1 | METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYCARBAMATE | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-23 | — | — | US | disclosed |
| EP-2752405-A1 | METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYAMINO FORMATE | Institute of Process Engineering, Chinese Academy of Sciences (CN) | 2014-07-09 | — | — | EP | disclosed |
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| EP-2322504-A1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2011-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | SMN1; SMN2 4254/4885CYP1A2 121/4885CYP2C19 132/4885 |
| US-20150038742-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | SMN1; SMN2 4254/4885CYP1A2 121/4885CYP2C19 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.