Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400826 | 0.91 | ALDH1A1 (0.64) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5006073 | 0.91 | L3MBTL1 (0.61) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11306455 | 0.90 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28401182 | 0.87 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28451035 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1839320 | 0.87 | SMN1; SMN2 (0.54) | ALDH1A1HPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL28834605 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7788545 | 0.87 | RAB9A (0.56) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18231364 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8867010 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846971-B2 | Metal carbamates formed from diaminophenylmethane | BASF SE (DE) | 2014-09-30 | — | — | US | claimed |
| US-20130281727-A1 | METAL CARBAMATES FORMED FROM DIAMINOPHENYLMETHANE | BASF SE (DE) | 2013-10-24 | — | — | US | claimed |
| EP-2265572-B1 | METAL CARBAMATES FORMED FROM DIAMINOPHENYLMETHANE | BASF SE (DE) | 2012-07-18 | — | — | EP | claimed |
| US-20110015424-A1 | METAL CARBAMATES FORMED FROM DIAMINOPHENYLMETHANE | BASF SE (DE) | 2011-01-20 | — | — | US | claimed |
| EP-2265572-A1 | METAL CARBAMATES FORMED FROM DIAMINOPHENYLMETHANE | BASF SE (DE) | 2010-12-29 | — | — | EP | claimed |
| WO-2009115537-A1 | METAL CARBAMATES FORMED FROM DIAMINOPHENYLMETHANE | BASF SE (DE) | 2009-09-24 | — | — | WO | claimed |
| US-4567287-A | Preparation of carbamates from organic carbonates and aromatic ureas | THE UPJOHN CO. (US) | 1986-01-28 | — | — | US | claimed |
| EP-2752405-B1 | METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYAMINO FORMATE | INST PROCESS ENG CAS (CN) | 2018-08-22 | — | — | EP | disclosed |
| EP-2322504-B9 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-2322504-B1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-9249090-B2 | N-substituted carbamic acid ester production method and isocyanate production method using the N-substituted carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-02-02 | — | — | US | disclosed |
| US-9062161-B2 | Method for preparing polymethylene polyphenyl polycarbamate | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2015-06-23 | — | — | US | disclosed |
| US-20150038742-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-02-05 | — | — | US | disclosed |
| US-20140316100-A1 | METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYCARBAMATE | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-23 | — | — | US | disclosed |
| EP-2752405-A1 | METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYAMINO FORMATE | Institute of Process Engineering, Chinese Academy of Sciences (CN) | 2014-07-09 | — | — | EP | disclosed |
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| EP-2322504-A1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2011-05-18 | — | — | EP | disclosed |
| EP-0881213-B1 | Process for the synthesis of aromatic urethanes | MINI RICERCA SCIENT TECNOLOG (IT) | 2001-09-19 | — | — | EP | disclosed |
| US-6034265-A | REACTING A CARBONATE WITH AROMATIC AMINE | MINISTERO DELL'UNIVERSITA E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 2000-03-07 | — | — | US | disclosed |
| EP-0881213-A2 | Process for the synthesis of aromatic urethanes | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1998-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015424-A1 | METAL CARBAMATES FORMED FROM DIAMINOPHENYLMETHANE | ARG1, PRMT1, PRMT3 | ALDH1A1 1450/4885HPGD 4268/4885CYP1A2 1183/4885 |
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | ALDH1A1 574/4885HPGD 703/4885CYP1A2 121/4885 |
| US-20150038742-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | ALDH1A1 574/4885HPGD 703/4885CYP1A2 121/4885 |
| US-20130281727-A1 | METAL CARBAMATES FORMED FROM DIAMINOPHENYLMETHANE | ARG1, PRMT1, PRMT3 | ALDH1A1 1450/4885HPGD 4268/4885CYP1A2 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.