Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18396241 | 1.00 | CYP2C9 (0.44) | CYP2C9LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL18395251 | 0.81 | MAOA (0.32) | MAPTALDH1A1KDM4EL3MBTL1GLA | |
| SCHEMBL18395250 | 0.81 | MAOA (0.32) | MAPTALDH1A1KDM4EL3MBTL1GLA | |
| SCHEMBL27775481 | 0.77 | CYP2C9 (0.49) | CYP2C9LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL18394956 | 0.76 | ALDH1A1 (0.37) | CYP2C9LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL18394954 | 0.76 | ALDH1A1 (0.37) | CYP2C9LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL18394936 | 0.75 | MAPT (0.43) | CYP2C9LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL18394935 | 0.75 | MAPT (0.43) | CYP2C9LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL1758445 | 0.74 | CYP2C9 (0.53) | CYP2C9LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL1758444 | 0.74 | CYP2C9 (0.53) | CYP2C9LMNAHPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10077323-B2 | Polymers functionalized with imine compounds containing a protected thiol group | BRIDGESTONE CORPORATION (JP) | 2018-09-18 | — | — | US | disclosed |
| US-20170022301-A1 | POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A PROTECTED THIOL GROUP | BRIDGESTONE CORPORATION (JP) | 2017-01-26 | — | — | US | disclosed |