Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 8/20 | 0.43 |
| ▸ | HRH1 | P35367 | 7/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731981 | 0.86 | HDAC1 (0.47) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14963898 | 0.84 | HTR6 (0.57) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL18399356 | 0.83 | HDAC1 (0.43) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2187740 | 0.82 | HDAC6 (0.49) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2187941 | 0.79 | HTR6 (0.50) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL18399355 | 0.78 | HDAC1 (0.46) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2187729 | 0.78 | HDAC1 (0.49) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL169856 | 0.78 | HRH1 (0.55) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14728963 | 0.77 | GRIN2D (0.51) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13293495 | 0.76 | HDAC1 (0.41) | HDAC1HDAC6GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550782-B2 | Compounds and methods for treating diabetes | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-01-24 | — | — | US | disclosed |