SCHEMBL18401282

SCHEMBL18401282

CN1CCN(CC2CCCCCCCCCC2)C1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.56
ADRA2C P18825 1/20 0.56
ACHE P22303 1/20 0.53
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM1 P11229 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CASP1 P29466 1/20 0.38
CASP4 P49662 1/20 0.38
CASP5 P51878 1/20 0.38
SIGMAR1 Q99720 3/20 0.38
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
OPRM1 P35372 2/20 0.36
OPRL1 P41146 2/20 0.36
OPRK1 P41145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18401417 1.00 CHRM5 (0.56) CHRM5ADRA2CACHECHRM2CHRM4
SCHEMBL22422525 1.00 CHRM5 (0.56) CHRM5ADRA2CACHECHRM2CHRM4
SCHEMBL21650864 0.98 CHRM5 (0.52) CHRM5ADRA2CACHECHRM2CHRM4
SCHEMBL2616298 0.89 CHRM5 (0.39) CHRM5ADRA2CACHE
SCHEMBL1777579 0.87 CHRM5 (0.67) CHRM5ADRA2CACHECHRM2CHRM4
SCHEMBL12772838 0.85 CHRM5 (0.62) CHRM5ADRA2CACHECHRM2CHRM4
SCHEMBL2616300 0.80 CHRM5 (0.56) CHRM5ADRA2CACHESMN1; SMN2CASP1
SCHEMBL5376134 0.79 CHRM5 (0.84) CHRM5ADRA2CACHECHRM2CHRM4
SCHEMBL11596303 0.79 CHRM5 (0.84) CHRM5ADRA2CACHECHRM2CHRM4
SCHEMBL22783243 0.78 CHRM5 (0.48) CHRM5ADRA2CACHECHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9550704-B2 Method for synthesizing radiopharmaceuticals using a cartridge FUTURECHEM CO., LTD. (KR) 2017-01-24 US disclosed