SCHEMBL5376134

SCHEMBL5376134

C1CCC(CN2CCN(CC3CCCCC3)CCN(CC3CCCCC3)CC2)CC1

nearest known ligand 0.84

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.84
ADRA2C P18825 1/20 0.84
ACHE P22303 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.53
CHRM2 P08172 1/20 0.52
CHRM4 P08173 1/20 0.52
CHRM1 P11229 1/20 0.52
CASP1 P29466 1/20 0.50
CASP4 P49662 1/20 0.50
CASP5 P51878 1/20 0.50
OPRM1 P35372 3/20 0.46
OPRL1 P41146 3/20 0.46
OPRD1 P41143 1/20 0.46
OPRK1 P41145 1/20 0.46
TRPC5 Q9UL62 1/20 0.44
SIGMAR1 Q99720 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596303 1.00 CHRM5 (0.84) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL3439903 0.92 CHRM5 (0.90) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL1515104 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL18361231 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL30340995 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL3439882 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL19575409 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL18616997 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2
SCHEMBL20643257 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2
Leptacline SCHEMBL509769 0.92 CHRM5 (1.00) CHRM5ADRA2CACHESMN1; SMN2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7161000-B2 Method for producing phenol condensate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-09 US disclosed
US-20040267057-A1 Method for producing phenol condensate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040267057-A1 Method for producing phenol condensate SOD1, MLX, XDH CHRM5 472/4885ADRA2C 4462/4885ACHE 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.