SCHEMBL22783243

SCHEMBL22783243

CCCN1CCN(CC2CCCC2)C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.48
ADRA2C P18825 1/20 0.48
ACHE P22303 1/20 0.47
OPRM1 P35372 2/20 0.36
OPRL1 P41146 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CYP1A2 P05177 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
DRD1 P21728 1/20 0.34
DRD4 P21917 1/20 0.34
DRD5 P21918 1/20 0.34
DRD3 P35462 1/20 0.34
CASP1 P29466 1/20 0.34
CASP4 P49662 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24723958 0.86 CHRM5 (0.61) CHRM5ADRA2CACHEOPRM1OPRL1
SCHEMBL21085341 0.83 CHRM5 (0.52) CHRM5ADRA2CACHEOPRM1OPRL1
SCHEMBL21084889 0.80 CHRM5 (0.48) CHRM5ADRA2CACHEOPRM1OPRL1
SCHEMBL21650864 0.79 CHRM5 (0.52) CHRM5ADRA2CACHEOPRM1OPRL1
SCHEMBL12717798 0.79 CHRM5 (0.44) CHRM5ADRA2CACHEDRD2
SCHEMBL18401417 0.78 CHRM5 (0.56) CHRM5ADRA2CACHEOPRM1OPRL1
SCHEMBL22422525 0.78 CHRM5 (0.56) CHRM5ADRA2CACHEOPRM1OPRL1
SCHEMBL18401282 0.78 CHRM5 (0.56) CHRM5ADRA2CACHEOPRM1OPRL1
SCHEMBL8526350 0.78 DRD2 (0.43) MAPTDRD2DRD3
SCHEMBL16892332 0.75 DRD2 (0.41) MAPTDRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3453038-B1 ELECTROACTIVE IONIC LIQUIDS AND SURFACE-MODIFIED SUBSTRATES CONTAINING THEM CENTRE NAT RECH SCIENT (FR) 2020-12-16 EP disclosed