Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368959 | 0.80 | CA1 (0.48) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL12570472 | 0.80 | MMP1 (0.50) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL9732244 | 0.78 | CA1 (0.46) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL2174854 | 0.77 | CA1 (0.46) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL11764655 | 0.76 | CA1 (0.45) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL1899031 | 0.73 | TP53 (0.52) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL8117812 | 0.72 | PSEN1 (0.45) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL16232170 | 0.72 | MMP2 (0.50) | CA1CA2PSEN1PSEN2APH1B | |
| SCHEMBL1980896 | 0.71 | SLC1A3 (0.51) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL16232171 | 0.71 | PSEN1 (0.44) | CA1CA2PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9553326-B2 | Aromatic sulfonic acid derivative, sulfonic acid group-containing polymer, block copolymer, polymer electrolyte material, polymer electrolyte form article, and polymer electrolyte fuel cell | TORAY INDUSTRIES, INC. (JP) | 2017-01-24 | — | — | US | disclosed |