Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269284 | 0.88 | NAAA (0.36) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10269001 | 0.85 | PDE4B (0.41) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL18499823 | 0.84 | L3MBTL1 (0.33) | — | |
| SCHEMBL10269287 | 0.83 | PDE4B (0.41) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10269283 | 0.83 | PDE4B (0.40) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10269286 | 0.77 | PDE4B (0.37) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL18402864 | 0.76 | CHRM1 (0.32) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10213995 | 0.76 | KDM4C (0.31) | — | |
| SCHEMBL10269285 | 0.75 | PDE4B (0.39) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL18500995 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549938-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2017-01-24 | — | — | US | disclosed |