Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150359 | 0.80 | PDK2 (0.52) | ALDH1A1LMNAPDK2PDK4PGR | |
| SCHEMBL9608370 | 0.69 | PNMT (0.39) | CYP1A2HPGDHSD17B10KDM4EPARP1 | |
| SCHEMBL2270532 | 0.67 | PDK2 (0.53) | ALDH1A1PDK2PDK4PGRKMT2A | |
| SCHEMBL24112426 | 0.67 | PDK2 (0.53) | PDK2PDK4PGRMAOB | |
| SCHEMBL18403203 | 0.67 | PNMT (0.43) | CYP1A2HPGDHSD17B10KDM4EPARP1 | |
| SCHEMBL16107538 | 0.66 | IDO1 (0.65) | CYP1A2HPGDHSD17B10KDM4EPARP1 | |
| SCHEMBL28327 | 0.66 | IDO1 (0.73) | CYP1A2HPGDHSD17B10KDM4EPARP1 | |
| SCHEMBL4869305 | 0.66 | IDO1 (0.73) | CYP1A2HPGDHSD17B10KDM4EPARP1 | |
| SCHEMBL29351230 | 0.66 | IDO1 (0.73) | CYP1A2HPGDHSD17B10KDM4EPARP1 | |
| SCHEMBL3149249 | 0.66 | PDK2 (0.52) | PDK2PDK4PGRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |