Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608366 | 0.70 | PNMT (0.44) | PNMTCYP1A2HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL18403201 | 0.69 | CYP1A2 (0.42) | PNMTCYP1A2HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL9608368 | 0.68 | PNMT (0.49) | PNMTCYP1A2HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL9608363 | 0.67 | PNMT (0.60) | PNMTCYP1A2HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL27532014 | 0.66 | BCL2L1 (0.60) | PNMTCYP1A2HSD17B10ALDH1A1HPGD | |
| SCHEMBL16107538 | 0.65 | IDO1 (0.65) | PNMTCYP1A2HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL4869305 | 0.65 | IDO1 (0.73) | CYP1A2HSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL28327 | 0.65 | IDO1 (0.73) | CYP1A2HSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL29351230 | 0.65 | IDO1 (0.73) | CYP1A2HSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL10298962 | 0.64 | HPGD (0.52) | PNMTCYP1A2HSD17B10ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160122813-A1 | Methods And Kits Using Extended Rhodamine Dyes | THE PERKIN-ELMER CORPORATION | 2016-05-05 | — | — | US | disclosed |
| US-9309561-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140171336-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2014-06-19 | — | — | US | disclosed |
| US-8628975-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-20120135885-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2012-05-31 | — | — | US | disclosed |
| US-8124746-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110053282-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2011-03-03 | — | — | US | disclosed |
| US-7776568-B2 | Rhodamine dye compounds for patterns with DNA sequences for kits | APPLIED BIOSYSTEMS, LLC (US) | 2010-08-17 | — | — | US | disclosed |