Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016032 | 0.66 | TSHR (0.32) | TSHRHSD17B10KMT2A | |
| SCHEMBL11858614 | 0.66 | — | — | |
| SCHEMBL8837708 | 0.66 | TSHR (0.36) | TSHRHSD17B10KMT2A | |
| SCHEMBL11312589 | 0.65 | TSHR (0.33) | TSHRHSD17B10KMT2A | |
| Imidazole SCHEMBL28764497 | 0.65 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL30395295 | 0.65 | TSHR (0.31) | TSHRHSD17B10KMT2A | |
| SCHEMBL29232749 | 0.65 | TSHR (0.35) | TSHRHSD17B10KMT2A | |
| SCHEMBL22784198 | 0.64 | CYP1A2 (0.37) | CYP4F2CYP4A11TSHRCYP1A2ALDH1A1 | |
| SCHEMBL28621880 | 0.64 | TSHR (0.41) | TSHRHSD17B10KMT2A | |
| SCHEMBL4702420 | 0.64 | CYP1A2 (0.45) | CYP4F2CYP4A11TSHRKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202223-B1 | HETEROCYCLIC COMPOUND AS BLOOD RBP4 LOWERING AGENT | TAKEDA PHARMACEUTICALS CO (JP) | 2017-01-25 | — | — | EP | disclosed |