Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 10/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18404253 | 0.79 | RBP4 (0.58) | RBP4CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL3105695 | 0.75 | RBP4 (0.74) | RBP4TTRALDH1A1ATMTDP1 | |
| SCHEMBL22023666 | 0.74 | RBP4 (0.53) | RBP4CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL3108232 | 0.74 | RBP4 (0.57) | RBP4CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL3105351 | 0.72 | RBP4 (0.55) | RBP4L3MBTL1GAA | |
| SCHEMBL3094503 | 0.72 | RBP4 (0.69) | RBP4ALDH1A1ATMTDP1 | |
| SCHEMBL17955427 | 0.72 | RBP4 (0.52) | RBP4CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL23665229 | 0.72 | RBP4 (0.51) | RBP4CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL22702793 | 0.72 | RBP4 (0.51) | RBP4CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL13299698 | 0.71 | RBP4 (0.75) | RBP4TTRALDH1A1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202223-B1 | HETEROCYCLIC COMPOUND AS BLOOD RBP4 LOWERING AGENT | TAKEDA PHARMACEUTICALS CO (JP) | 2017-01-25 | — | — | EP | disclosed |