Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20313308 | 1.00 | PARP1 (0.46) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL23815322 | 0.83 | PARP1 (0.48) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL25732483 | 0.79 | PRSS1 (0.48) | ALDH1A1HPGD | |
| SCHEMBL24710508 | 0.78 | TDP1 (0.50) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL19288105 | 0.78 | PARP1 (0.47) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL17117831 | 0.78 | PARP1 (0.40) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL17273799 | 0.77 | F2 (0.42) | ACHEALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL11813974 | 0.77 | GPR52 (0.56) | PARP1HDAC8HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL1348921 | 0.77 | GPR52 (0.56) | PARP1HDAC8HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL11813977 | 0.77 | GPR52 (0.56) | PARP1HDAC8HDAC6SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509602-B1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | SENHWA BIOSCIENCES INC (TW) | 2017-01-25 | — | — | EP | disclosed |