Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945625 | 0.92 | CA2 (0.37) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL6535041 | 0.92 | MAOA (0.44) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL9612246 | 0.90 | MAOA (0.43) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL25683487 | 0.86 | MAOA (0.39) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL3297916 | 0.84 | MAOA (0.40) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL783009 | 0.83 | CA2 (0.41) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL12450077 | 0.82 | MAOA (0.39) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL22235058 | 0.82 | MAOA (0.39) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL3809747 | 0.82 | MAOA (0.39) | MAOAMAOBCA12CA2CA14 | |
| SCHEMBL16558051 | 0.82 | MAOA (0.41) | MAOAMAOBCA12CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | FIVE ELEVEN PHARMA INC. | 2017-07-06 | — | — | US | disclosed |
| US-20170022224-A1 | HBED-Bisphosphonates, Radiometal Conjugates and Their Use as Theranostic Agents | FIVE ELEVEN PHARMA INC. (US) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | KLK3, FOLH1, UTS2R | MAOA 4304/4885MAOB 3912/4885CA12 250/4885 |
| US-20170022224-A1 | HBED-Bisphosphonates, Radiometal Conjugates and Their Use as Theranostic Agents | SLC10A1, SLC9B2, SLCO2B1 | MAOA 4459/4885MAOB 3094/4885CA12 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.