Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 9/20 | 0.58 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415631 | 0.96 | PTPN1 (0.61) | CYP2C9EYA3PTPN1TTRNR1H4 | |
| SCHEMBL2944813 | 0.86 | PTPN1 (0.69) | EYA3PTPN1TTRNR1H4THRA | |
| SCHEMBL18407416 | 0.85 | ALDH1A1 (0.58) | CYP2C9EYA3PTPN1TTR | |
| Hydrochloric Acid SCHEMBL9347277 | 0.85 | PTPN1 (0.67) | EYA3PTPN1TTRNR1H4THRA | |
| SCHEMBL9760347 | 0.84 | CYP2C9 (0.68) | CYP2C9EYA3PTPN1TTRNR1H4 | |
| SCHEMBL29096698 | 0.84 | EYA3 (0.60) | CYP2C9EYA3PTPN1TTRNR1H4 | |
| SCHEMBL957193 | 0.82 | PTPN1 (0.53) | CYP2C9EYA3PTPN1TTR | |
| SCHEMBL11785448 | 0.82 | EYA3 (0.64) | CYP2C9EYA3PTPN1TTRNR1H4 | |
| SCHEMBL19732866 | 0.81 | PTPN1 (0.52) | CYP2C9EYA3PTPN1TTR | |
| SCHEMBL31314563 | 0.80 | EYA3 (0.61) | CYP2C9EYA3PTPN1TTRNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022165-A1 | PQSR MODULATORS | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022165-A1 | PQSR MODULATORS | QARS1, SRPRA, MRPS35 | CYP2C9 2135/4885EYA3 3012/4885PTPN1 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.