SCHEMBL1840917

SCHEMBL1840917

CCCCc1cccc(OC(=O)O)c1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.48
PPARG P37231 2/20 0.48
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1156862 0.96 PPARA (0.53) PPARAPPARGTHRATHRBALOX5
SCHEMBL1156635 0.94 PPARA (0.55) PPARAPPARGTHRATHRBALOX5
SCHEMBL27502230 0.94 PPARA (0.55) PPARAPPARGTHRATHRBALOX5
SCHEMBL1837756 0.94 PPARA (0.55) PPARAPPARGTHRATHRBALOX5
SCHEMBL1156919 0.94 PPARA (0.55) PPARAPPARGTHRATHRBALOX5
SCHEMBL1955605 0.94 PPARA (0.55) PPARAPPARGTHRATHRBALOX5
SCHEMBL1834263 0.91 LTB4R (0.41) PPARAPPARGTHRATHRBKDM4E
SCHEMBL1834116 0.89 PPARA (0.44) PPARAPPARGTHRATHRBALOX5
SCHEMBL27570045 0.88 PPARA (0.45) PPARAPPARGTHRATHRBALOX5
Biphenyl SCHEMBL17473017 0.87 THRA (0.56) PPARAPPARGTHRATHRBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
EP-3707198-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY Covestro Deutschland AG (DE) 2020-09-16 EP disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
CN-106536630-B Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties 科思创德国股份有限公司 2019-07-19 CN disclosed
CN-109153776-A Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2019-01-04 CN disclosed
EP-3153499-B1 METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2018-09-19 EP disclosed
EP-2322504-B9 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2017-09-06 EP disclosed
CN-106661318-A Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties 科思创德国股份有限公司 2017-05-10 CN disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
CN-1454914-A Makrolan having specific branching end group, polyester carbonate ester and polyester BAYER AG (DE) 2003-11-12 CN disclosed
US-6646099-B2 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
CN-1394895-A Preparation and use of polyester carbonic acid ester BAYER AG (DE) 2003-02-05 CN disclosed
CN-1390872-A polycarbonates, polyester carbonates and polyesters having branched end groups BAYER AG (DE) 2003-01-15 CN disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed