Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.39 |
| ▸ | ABL1 | P00519 | 11/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18409251 | 1.00 | MAP4K1 (0.39) | MAP4K1ABL1LRRK2 | |
| SCHEMBL18409254 | 0.89 | RAB9A (0.39) | MAP4K1ABL1 | |
| SCHEMBL18409609 | 0.85 | ABL1 (0.41) | MAP4K1ABL1LRRK2 | |
| SCHEMBL18409253 | 0.84 | ALDH1A1 (0.50) | ABL1 | |
| SCHEMBL18409415 | 0.79 | TYK2 (0.39) | MAP4K1ABL1 | |
| SCHEMBL18409161 | 0.79 | TYK2 (0.39) | MAP4K1ABL1 | |
| SCHEMBL18409165 | 0.78 | ABL1 (0.42) | MAP4K1ABL1LRRK2 | |
| SCHEMBL18409168 | 0.78 | ABL1 (0.41) | MAP4K1ABL1LRRK2 | |
| SCHEMBL18409435 | 0.76 | JAK2 (0.37) | MAP4K1ABL1LRRK2 | |
| SCHEMBL18409540 | 0.76 | JAK2 (0.47) | MAP4K1ABL1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017012647-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2017-01-26 | — | — | WO | disclosed |