Terephthalic Acid

Terephthalic Acid

SCHEMBL184129

O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
DAO P14920 1/20 0.68
NAPRT Q6XQN6 1/20 0.68
TP53 P04637 1/20 0.67
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA6 P23280 2/20 0.65
CA9 Q16790 2/20 0.65
SRD5A2 P31213 2/20 0.64
CES2 O00748 1/20 0.64
CES1 P23141 1/20 0.64
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
KMO O15229 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2C9 P11712 1/20 0.60
HPGD P15428 1/20 0.60
HSD17B10 Q99714 1/20 0.60
UNG P13051 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL4872836 1.00 TSHR (0.68) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10927557 1.00 TSHR (0.68) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL28523263 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL20545275 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL20545273 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10420586 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10905833 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10597727 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL3070285 0.95 TSHR (0.62) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL11855013 0.95 TSHR (0.62) TSHRDAONAPRTTP53CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12000091-B2 Polymer coated paper and paperboard STORA ENSO OYJ (FI) 2024-06-04 US claimed
EP-3024875-B1 PROCESS FOR THE PURIFICATION OF POLYCARBONATE SHPP GLOBAL TECH BV (NL) 2023-12-20 EP claimed
EP-3024876-B1 THERMAL ENHANCEMENT OF THE PURIFICATION PROCESS FOR INTERFACIAL POLYCARBONATE AND COPOLYMER POLYCARBONATES SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-11-22 EP claimed
WO-2023031828-A1 FILLED CONDUCTIVE COMPOSITIONS WITH IMPROVED ELECTRICAL CONDUCTIVITY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-03-09 WO claimed
US-11299637-B2 Weather-resistant temporary paint system comprising a removable paint composition and a remover composition Renu TPS Limited (GB) 2022-04-12 US claimed
EP-3931258-A1 COMPOSITIONS HAVING IMPROVED CHEMICAL RESISTANCE, ARTICLES FORMED THEREOF, AND METHODS OF MANUFACTURE SHPP Global Technologies B.V. (NL) 2022-01-05 EP claimed
US-20210317612-A1 POLYMER COATED PAPER AND PAPERBOARD STORA ENSO OYJ (FI) 2021-10-14 US claimed
EP-3031861-B1 POLYESTER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-01-08 EP claimed
CN-110214379-A Conductive copolyestercarbonate-based materials 沙特基础工业全球技术公司 2019-09-06 CN claimed
US-9938543-B2 Methods, reagents and cells for biosynthesizing glutarate methyl ester INVISTA NORTH AMERICA S.A.R.L. (US) 2018-04-10 US claimed
EP-0049940-A1 Solvent-free wire enamel blends, UV-curable to the B-stage WESTINGHOUSE ELECTRIC CORPORATION (US) 1982-04-21 EP claimed
US-4317858-A ACRYLATED EPOXY RESINS, POLYBUTADIENE, POLYESTER-AMIDE-IMIDE, ENDBLOCKED URETHANE, CRESOL-FORMALDE-HYDE RESIN AND AN ACRYLATED METHOXYMETHYL MELAMINE WESTINGHOUSE ELECTRIC CORP. (US) 1982-03-02 US claimed
EP-0030414-A1 Thermoplastic polymer compositions and shaped articles formed therefrom OCCIDENTAL CHEMICAL CORPORATION (US) 1981-06-17 EP claimed
US-4268661-A INJECTION MOLDING INVENTA AG FUR FORSCHUNG UND PATENTVERWERTUNG, ZURICH (CH) 1981-05-19 US claimed
US-4232145-A FROM A DIAMINODICYCLO-HEXANE OR -HEXYLALKANE, ISOPHTHALIC ACID, AND AN OMEGA-AMINOALKANOIC ACID; CHAIN EXTENSION INVENTA AG FUR FORSCHUNG UND PATENTVERWERTUNG, ZURICH (CH) 1980-11-04 US claimed
EP-0007171-A1 Polymer compositions, molded articles and films with improved hydrolytic stability HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-01-23 EP claimed
US-4093590-A METAL SALTS OF MONOMERIC OR POLYMERIC PHENOL ESTER SULFONIC ACIDS GENERAL ELECTRIC COMPANY (US) 1978-06-06 US claimed
US-4011358-A PRESSURE SENSITIVE ADHESIVE TAPES, LITHOGRAPHIC PRINTING PLATES, COATED ABRASIVES, SPLICING TAPES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-03-08 US claimed
US-3969306-A POLYBUTADIENE GENERAL ELECTRIC COMPANY (US) 1976-07-13 US claimed
US-3936400-A Flame retardant foamed polyester compositions GENERAL ELECTRIC COMPANY (US) 1976-02-03 US claimed