Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KMO | O15229 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL10927557 | 0.97 | TSHR (0.68) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL4872836 | 0.97 | TSHR (0.68) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL184129 | 0.97 | TSHR (0.68) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL10905833 | 0.95 | TSHR (0.65) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL20545273 | 0.95 | TSHR (0.65) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL20545275 | 0.95 | TSHR (0.65) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL10420586 | 0.95 | TSHR (0.65) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL10597727 | 0.95 | TSHR (0.65) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL3070285 | 0.92 | TSHR (0.62) | TSHRDAONAPRTTP53CA12 | |
| Terephthalic Acid SCHEMBL11855013 | 0.92 | TSHR (0.62) | TSHRDAONAPRTTP53CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112403473-B | Synthesis method for preparing reforming catalyst through MOFs | 上海簇睿低碳能源技术有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-112403473-A | Synthetic method for preparing reforming catalyst through MOFs | 上海簇睿低碳能源技术有限公司 | 2021-02-26 | — | — | CN | disclosed |