Terephthalic Acid

Terephthalic Acid

SCHEMBL4872836

O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
DAO P14920 1/20 0.68
NAPRT Q6XQN6 1/20 0.68
TP53 P04637 1/20 0.67
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA6 P23280 2/20 0.65
CA9 Q16790 2/20 0.65
SRD5A2 P31213 2/20 0.64
CES2 O00748 1/20 0.64
CES1 P23141 1/20 0.64
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
KMO O15229 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2C9 P11712 1/20 0.60
HPGD P15428 1/20 0.60
HSD17B10 Q99714 1/20 0.60
UNG P13051 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL184129 1.00 TSHR (0.68) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10927557 1.00 TSHR (0.68) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL28523263 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL20545275 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL20545273 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10420586 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10905833 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL10597727 0.97 TSHR (0.65) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL3070285 0.95 TSHR (0.62) TSHRDAONAPRTTP53CA12
Terephthalic Acid SCHEMBL11855013 0.95 TSHR (0.62) TSHRDAONAPRTTP53CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374384-A1 POLYMER COMPOUND, COMPOSITION, AND MOLDED PRODUCT FUJIFILM CORPORATION (JP) 2023-11-23 US disclosed
WO-2023167054-A1 RESIN COMPOSITION FOR FIBER-REINFORCED MOLDED COMPOSITE OBJECT, AND FIBER-REINFORCED MOLDED COMPOSITE OBJECT 帝人株式会社 2023-09-07 WO disclosed
CN-113383035-B Molding material comprising carbon fiber-reinforced polycarbonate resin composition 帝人株式会社 2023-08-01 CN disclosed
WO-2022181513-A1 POLYMERIC COMPOUND, COMPOSITION, AND MOLDED ARTICLE 富士フイルム株式会社 2022-09-01 WO disclosed
WO-2020158293-A1 MOLDING MATERIAL COMPRISING CARBON FIBER-REINFORCED POLYCARBONATE RESIN COMPOSITION 帝人株式会社 2020-08-06 WO disclosed
CN-105051110-B Glass fiber-reinforced poly carbonate resin composition 帝人株式会社 2018-05-25 CN disclosed
CN-105051110-A Glass-fiber-reinforced polycarbonate resin composition TEIJIN LTD 2015-11-11 CN disclosed
CN-101514256-A Resin molding material TEIJIN CHEMICALS LTD (JP) 2009-08-26 CN disclosed
CN-101514257-A Electroconductive resin molding material TEIJIN CHEMICALS LTD (JP) 2009-08-26 CN disclosed
CN-101381510-A Thermoplastic resin compositions TEIJIN CHEMICALS LTD (JP) 2009-03-11 CN disclosed
US-7371455-B2 Laminates and packaging containers KYDO PRINTING CO., LTD. (JP) 2008-05-13 US disclosed
US-7118800-B2 Skin layer with a glass transition point of 85-115 degrees C.composed of a copolymer of 2,6-naphthalenedicarboxylic acid, terephthalic acid and ethylene glycol or an alloy of polyethylene terephthalate and polyethylene-2,6-naphthalate; core layer of thermoplastic polyester/heat resistant resin alloy KYODO PRINTING CO., LTD. (JP) 2006-10-10 US disclosed
US-20060204695-A1 Laminates and packaging containers KYODO PRINTING CO., LTD. (JP) 2006-09-14 US disclosed
US-20050084695-A1 Laminates and packaging containers KYODO PRINTING CO., LTD. (JP) 2005-04-21 US disclosed
CN-1589202-A laminate and packaging container KYODO PRINTING CO LTD (JP) 2005-03-02 CN disclosed
EP-1447216-A1 LAMINATES AND PACKAGING CONTAINERS Kyodo Printing Co., Ltd. (JP) 2004-08-18 EP disclosed