Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 7/20 | 0.48 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392603 | 0.91 | SLC6A11 (0.48) | SLC6A11SLC6A1NPC1RAB9AHPGD | |
| SCHEMBL16357997 | 0.89 | SLC6A11 (0.47) | SLC6A11SLC6A1NPC1RAB9AHPGD | |
| SCHEMBL16392604 | 0.85 | DPP4 (0.45) | SLC6A11SLC6A1NPC1RAB9AHPGD | |
| SCHEMBL16392607 | 0.83 | PREP (0.49) | SLC6A11SLC6A1NPC1RAB9AMEN1 | |
| SCHEMBL10118446 | 0.83 | SLC6A11 (0.55) | SLC6A11SLC6A1MEN1KMT2ASLC6A12 | |
| SCHEMBL18857570 | 0.83 | SLC6A11 (0.48) | SLC6A11SLC6A1NPC1RAB9AHPGD | |
| SCHEMBL31606441 | 0.81 | SLC6A11 (0.43) | SLC6A11SLC6A1NPC1RAB9AHPGD | |
| SCHEMBL764125 | 0.81 | SLC6A11 (0.52) | SLC6A11SLC6A1MEN1KMT2ASLC6A12 | |
| SCHEMBL14615793 | 0.80 | DRD2 (0.48) | SLC6A11SLC6A1DPP4 | |
| SCHEMBL28349162 | 0.80 | SLC6A11 (0.44) | SLC6A11SLC6A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017015109-A1 | MULTI-TARGETED SINGLE ENTITY CONJUGATES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-01-26 | — | — | WO | disclosed |