Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18413652 | 0.83 | TGM2 (0.49) | TGM2CES1HTR6PDK2PDK4 | |
| SCHEMBL18413662 | 0.80 | CHEK1 (0.39) | HTR6MGAT2PDK2PDK4PGR | |
| SCHEMBL18413726 | 0.79 | PDE7A (0.36) | TGM2CES1HTR6MGAT2 | |
| SCHEMBL12237301 | 0.78 | PDK2 (0.53) | MGAT2PDK2PDK4MAPT | |
| SCHEMBL14207166 | 0.75 | AKR1B1 (0.37) | CES1HTR6MGAT2PDK2PDK4 | |
| SCHEMBL31238681 | 0.72 | PDK2 (0.55) | PDK2PDK4PGRPDE3BPDE3A | |
| SCHEMBL10116540 | 0.72 | PDK2 (0.55) | PDK2PDK4PGRPDE3BPDE3A | |
| SCHEMBL2144278 | 0.72 | PDK2 (0.55) | TGM2CES1HTR6PDK2PDK4 | |
| SCHEMBL12946119 | 0.69 | HTR6 (0.31) | HTR6MGAT2 | |
| SCHEMBL3594073 | 0.68 | MGAT2 (0.37) | MGAT2PDK2PDK4PGRPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190091673-A1 | DISSOCIABLE NANOPARTICLES WITH INTER ALIA TRANSITION-METAL COMPLEX CATALYSTS | OXFORD FINANCE LLC | 2019-03-28 | — | — | US | disclosed |
| WO-2017015145-A2 | DISSOCIABLE TRANSITION-METAL NANOPARTICLES | SeLux Diagnostics, Inc. (US) | 2017-01-26 | — | — | WO | disclosed |