SCHEMBL18418

SCHEMBL18418

CN1C=CC(c2c3nc(c(C4=CCN(C)C=C4)c4ccc([nH]4)c(C4=CCN(C)C=C4)c4nc(c(C5=CCN(C)C=C5)c5ccc2[nH]5)C=C4)C=C3)=CC1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TERT O14746 3/20 0.44
TOP1 P11387 3/20 0.38
CYCS P99999 2/20 0.36
ENPP2 Q13822 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29677253 1.00 TERT (0.44) TERTTOP1CYCSENPP2
Hydrochloric Acid SCHEMBL4138914 0.98 TERT (0.43) TERTTOP1CYCSENPP2
Bromide SCHEMBL4128664 0.98 TERT (0.43) TERTTOP1CYCSENPP2
SCHEMBL30417480 0.98 TERT (0.43) TERTTOP1CYCSENPP2
Hydrochloric Acid SCHEMBL30474599 0.98 TERT (0.43) TERTTOP1CYCSENPP2
Hydrochloric Acid SCHEMBL7246124 0.98 TERT (0.43) TERTTOP1CYCSENPP2
SCHEMBL4126389 0.94 TERT (0.40) TERTTOP1CYCSENPP2
Acetic Acid SCHEMBL9073655 0.92 TOP1 (0.44) TERTTOP1CYCSENPP2
SCHEMBL2535689 0.91 TERT (0.47) TERTTOP1CYCSENPP2
SCHEMBL9438544 0.91 TERT (0.47) TERTTOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250288653-A1 ARTIFICIAL BLOOD SUBSTITUTES CHANG THOMAS MING SWI (CA) 2025-09-18 US claimed
US-20160228356-A1 THE CONTINUOUS LONG-TERM CONTROLLED RELEASE OF TELOMERASE INHIBITORS LASTER, Brenda (IL) 2016-08-11 US claimed
WO-2015040622-A1 THE CONTINUOUS LONG-TERM CONTROLLED RELEASE OF TELOMERASE INHIBITORS LASTER BRENDA (IL) 2015-03-26 WO claimed
US-8501366-B1 Nanoengineered membrane electrode assembly interface SANDIA CORPORATION (US) 2013-08-06 US claimed
US-20120142623-A1 Compositions And Methods For Predicting Inhibitors Of Protein Targets UNIVERSITY OF WASHINGTON 2012-06-07 US claimed
EP-1401379-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2010-04-07 EP claimed
WO-2008006085-A2 COMPOSITIONS AND METHODS FOR PREDICTING INHIBITORS OF PROTEIN TARGETS UNIVERSITY OF WASHINGTON (US) 2008-01-10 WO claimed
US-20070248534-A1 Auger effect-based cancer therapy method BEN-GURION UNIVERSITY OF THE NEGEV (IL) 2007-10-25 US claimed
US-20050112058-A1 Auger effect-based cancer therapy method BEN-GURION UNIVERSITY OF THE NEGEV (IL) 2005-05-26 US claimed
WO-2004061416-A2 METHODS FOR ATTACHING MOLECULES GENORX, INC. (US) 2004-07-22 WO claimed
US-5702804-A Recording sheets XEROX CORPORATION (US) 1997-12-30 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US claimed
US-5271764-A Ink compositions XEROX CORPORATION (US) 1993-12-21 US claimed
US-5256193-A Porphyrin chromophore and dendrimer ink composition XEROX CORPORATION (US) 1993-10-26 US claimed
US-4986256-A MAGNETIC RESONANCE IMAGING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1991-01-22 US claimed
WO-1989011277-A2 PORPHYRIN AND PHTHALOCYANINE ANTIVIRAL COMPOSITIONS GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) 1989-11-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160228356-A1 THE CONTINUOUS LONG-TERM CONTROLLED RELEASE OF TELOMERASE INHIBITORS TERT, POT1, TERF2 TERT 1/4885TOP1 1486/4885CYCS 842/4885
US-20050112058-A1 Auger effect-based cancer therapy method LIG4, DNMT1, UNG TERT 1097/4885TOP1 36/4885CYCS 2086/4885
US-20070248534-A1 Auger effect-based cancer therapy method LIG4, DNMT1, UNG TERT 1097/4885TOP1 36/4885CYCS 2086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.