Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290359 | 0.84 | MEN1 (0.56) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL16825208 | 0.84 | ENPP2 (0.53) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL30719262 | 0.84 | GRIN2B (0.58) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL5255119 | 0.84 | SMN1; SMN2 (0.49) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL4717126 | 0.84 | SMN1; SMN2 (0.49) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL7424105 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL1000788 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL794423 | 0.82 | MEN1 (0.69) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL6557909 | 0.82 | MEN1 (0.69) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL4710641 | 0.82 | MEN1 (0.69) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192136-B1 | OLIGOMERS AND POLYMERS OF CYCLIC IMINO CARBOXYLIC ACIDS | WISCONSIN ALUMNI RES FOUND (US) | 2011-05-18 | — | — | EP | disclosed |
| US-7304165-B2 | Oligomers and polymers of di-substituted cyclic imino carboxylic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-12-04 | — | — | US | disclosed |
| US-6914048-B2 | Method for delivery of molecules to intracellular targets | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-07-05 | — | — | US | disclosed |
| US-20040152133-A1 | Oligomers and polymers of di-substituted cyclic imino carboxylic acids | GELLMAN SAMUEL H (US) | 2004-08-05 | — | — | US | disclosed |
| US-6727368-B1 | PYRROLIDINE-3-CARBOXYLIC ACID MONOMERS; POLYLACTAMS; COMBINATORIAL LIBRARIES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2004-04-27 | — | — | US | disclosed |
| US-6710186-B2 | CONFORMATIONALLY-RESTRICTED; ANALOGOUS TO POLY(PROLINE) II HELICAL STRUCTURE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2004-03-23 | — | — | US | disclosed |
| US-20030119189-A1 | Method for delivery of molecules to intracellular targets | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-26 | — | — | US | disclosed |
| WO-2003024477-A1 | METHOD FOR DELIVERY OF MOLECULES TO INTRACELLULAR TARGETS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2003-03-27 | — | — | WO | disclosed |
| EP-1192136-A2 | OLIGOMERS AND POLYMERS OF CYCLIC IMINO CARBOXYLIC ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2002-04-03 | — | — | EP | disclosed |
| US-20020032334-A1 | Oligomers and polymers of di-substituted cyclic imino carboxylic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2002-03-14 | — | — | US | disclosed |
| WO-2000076974-A2 | OLIGOMERS AND POLYMERS OF CYCLIC IMINO CARBOXYLIC ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2000-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032334-A1 | Oligomers and polymers of di-substituted cyclic imino carboxylic acids | PCNA, PAICS, INHA | MEN1 602/4885KMT2A 4828/4885NPSR1 1610/4885 |
| US-20040152133-A1 | Oligomers and polymers of di-substituted cyclic imino carboxylic acids | PCNA, PAICS, INHA | MEN1 602/4885KMT2A 4828/4885NPSR1 1610/4885 |
| US-20030119189-A1 | Method for delivery of molecules to intracellular targets | DNPEP, SLC7A1, PHAX | MEN1 1251/4885KMT2A 4644/4885NPSR1 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.