Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841981 | 0.84 | MEN1 (0.52) | GRIN2BLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4717126 | 0.83 | SMN1; SMN2 (0.49) | GRIN2BLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16825208 | 0.83 | ENPP2 (0.53) | LMNASMN1; SMN2ALDH1A1HCAR2MEN1 | |
| SCHEMBL5542082 | 0.83 | GRIN2B (0.53) | GRIN2BLMNASMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL28032629 | 0.82 | KMT2A (0.64) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL16825229 | 0.82 | GRIN2B (0.54) | GRIN2BSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL794423 | 0.82 | MEN1 (0.69) | GRIN2BLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6557909 | 0.82 | MEN1 (0.69) | GRIN2BLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4710641 | 0.82 | MEN1 (0.69) | GRIN2BLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5537533 | 0.81 | GRIN2B (0.52) | GRIN2BLMNAALDH1A1HCAR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304191-A | Fused pyrazine derivatives as A2A/A2B inhibitors | 因赛特公司 | 2023-12-29 | — | — | CN | disclosed |