SCHEMBL18421900

SCHEMBL18421900

O=S(=O)(c1ccccc1)N(SC(Cl)(Cl)CCl)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
PKM P14618 1/20 0.38
LMNA P02545 1/20 0.37
ESR1 P03372 3/20 0.36
KMT2A Q03164 3/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RORC P51449 1/20 0.35
MEN1 O00255 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27951833 0.83 CDK1 (0.43) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL4828287 0.83 CDK1 (0.43) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL25238002 0.77 APOBEC3G (0.42) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL18421901 0.76 ALDH1A1 (0.39) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL18421505 0.76 ESR1 (0.40) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL8038722 0.74 APOBEC3G (0.47) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL18421506 0.74 ALDH1A1 (0.37) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL8028854 0.71 APOBEC3G (0.47) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL18421807 0.70 ALDH1A1 (0.46) ALDH1A1APOBEC3GPKMLMNAESR1
SCHEMBL11118408 0.69 ALDH1A1 (0.37) ALDH1A1LMNAKMT2ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2023112393-A1 TIRE RUBBER COMPOSITION, AND TIRE 株式会社ブリヂストン 2023-06-22 WO disclosed
US-10059834-B2 Rubber vibration isolator composition and rubber vibration isolator BRIDGESTONE CORPORATION (JP) 2018-08-28 US disclosed
EP-3153545-A1 RUBBER VIBRATION DAMPENER COMPOSITION AND RUBBER VIBRATION DAMPENER Bridgestone Corporation (JP) 2017-04-12 EP disclosed
US-20170029602-A1 RUBBER VIBRATION ISOLATOR COMPOSITION AND RUBBER VIBRATION ISOLATOR BRIDGESTONE CORPORATION (JP) 2017-02-02 US disclosed