Nafenopin

Nafenopin

SCHEMBL184232

CC(C)(Oc1ccc(C2CCCc3ccccc32)cc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 1.00
MAPK14 Q16539 1/20 1.00
HAO1 Q9UJM8 1/20 0.53
PPARA Q07869 8/20 0.51
LMNA P02545 2/20 0.51
CYP2C9 P11712 2/20 0.51
TSHR P16473 1/20 0.51
BLM P54132 1/20 0.51
GID4 Q8IVV7 1/20 0.49
CYP2C19 P33261 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
PPARG P37231 6/20 0.43
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11603097 0.87 MAPK1 (0.77) MAPK1MAPK14HAO1PPARALMNA
SCHEMBL11754032 0.81 MAPK1 (0.69) MAPK1MAPK14HAO1BLMGID4
SCHEMBL11751775 0.80 MAPK1 (0.67) MAPK1MAPK14HAO1GID4CYP2D6
SCHEMBL11750267 0.80 MAPK1 (0.66) MAPK1MAPK14PPARALMNACYP2C9
SCHEMBL11750376 0.80 MAPK1 (0.66) MAPK1MAPK14HAO1LMNAGID4
Nafenopin SCHEMBL20770697 0.79 MAPK1 (0.63) MAPK1MAPK14LMNATSHRBLM
SCHEMBL1745291 0.78 MAPK1 (0.63) MAPK1MAPK14PPARALMNACYP2C9
SCHEMBL7324670 0.77 GID4 (0.72) MAPK1MAPK14HAO1GID4KMT2A
SCHEMBL13444088 0.77 GID4 (0.72) MAPK1MAPK14HAO1GID4KMT2A
SCHEMBL11749703 0.77 MAPK1 (0.63) MAPK1MAPK14PPARALMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 745 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122088761-A Analysis method for urban rail transit passenger travel path and riding scheme 2026-05-26 CN claimed
CN-120082612-A Method for preparing D-type rare hexulose by metabolic engineering modification of bacillus subtilis 江南大学 2025-06-03 CN claimed
CN-119979580-A Method for producing 1, 3-dihydroxyacetone 中国科学院天津工业生物技术研究所 2025-05-13 CN claimed
WO-2024220571-A2 METHODS AND COMPOSITIONS FOR DETECTING MICROBIAL GROWTH IN BUILT ENVIRONMENTS OHIO STATE INNOVATION FOUNDATION (US) 2024-10-24 WO claimed
CN-118038995-B Method and system for predicting small open reading window coding polypeptide capacity in non-coding RNA 常州大学 2024-08-23 CN claimed
CN-118147033-A Genetically engineered bacterium for high-yield of L-cysteine, construction method and application thereof 浙江工业大学 2024-06-07 CN claimed
CN-115820688-B Shewanella strain for synthesizing acetoin and bioelectricity by utilizing glycerol and construction method 天津大学 2024-05-31 CN claimed
CN-118038995-A Method and system for predicting small open reading window coding polypeptide capacity in non-coding RNA 常州大学 2024-05-14 CN claimed
CN-117737107-A Genetically engineered bacterium for synthesizing 4-coumaric acid and derivatives thereof, construction method and application thereof 徐州合谷生命科技有限公司 2024-03-22 CN claimed
CN-116836905-A Genetically engineered bacterium for high-yield of L-cysteine, construction method and application 浙江工业大学 2023-10-03 CN claimed
US-20030153619-A1 Applying on the skin, inhibiting fatty acid metabolism, using adriamycin, or enzyme inhibitors, dermatology GILLETTE COMPANY, THE 2003-08-14 US claimed
WO-2003063810-A2 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2003-08-07 WO claimed
JP-2003522787-A 2003-07-29 JP claimed
US-20030139372-A1 Modulation of bone formation UNIVERSITY OF SHEFFIELD (GB) 2003-07-24 US claimed
EP-1259233-A1 MODULATION OF BONE FORMATION THE UNIVERSITY OF SHEFFIELD (GB) 2002-11-27 EP claimed
WO-2001060355-A1 MODULATION OF BONE FORMATION UNIVERSITY OF SHEFFIELD (GB) 2001-08-23 WO claimed
CN-1104520-A Preparation method of oral liquid for relieving asthma and reducing blood fat HOU YUNSHAN (CN) 1995-07-05 CN claimed
EP-0556197-A4 PROLONGING EXPRESSION OF POLYNUCLEOTIDES INTRODUCED INTO A CELL UNIV CONNECTICUT (US) 1994-05-18 EP claimed
EP-0556197-A1 PROLONGING EXPRESSION OF POLYNUCLEOTIDES INTRODUCED INTO A CELL THE UNIVERSITY OF CONNECTICUT (US) 1993-08-25 EP claimed
WO-1992005250-A1 PROLONGING EXPRESSION OF POLYNUCLEOTIDES INTRODUCED INTO A CELL UNIVERSITY OF CONNECTICUT (US) 1992-04-02 WO claimed