SCHEMBL184235

SCHEMBL184235

CCCCCCCCCCCCN(C)C[C]=O

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.48
S1PR2 O95136 1/20 0.47
S1PR1 P21453 1/20 0.47
S1PR3 Q99500 1/20 0.47
S1PR5 Q9H228 1/20 0.47
GGPS1 O95749 4/20 0.44
KDM5A P29375 4/20 0.40
KDM4C Q9H3R0 3/20 0.40
PHF8 Q9UPP1 2/20 0.40
FDPS P14324 1/20 0.39
AGTR1 P30556 1/20 0.39
OPRM1 P35372 1/20 0.39
PDE3A Q14432 1/20 0.39
KDM5C P41229 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1461480 1.00 DNM1 (0.48) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL1462556 0.98 DNM1 (0.44) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL1462680 0.91
SCHEMBL1462568 0.80
SCHEMBL7346446 0.80 S1PR2 (0.50) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL9550792 0.79 DNM1 (0.44) DNM1KDM5AKDM4CPHF8TSHR
SCHEMBL7611885 0.79 DNM1 (0.44) DNM1KDM5AKDM4CPHF8TSHR
SCHEMBL1461490 0.79 DNM1 (0.44) DNM1KDM5AKDM4CPHF8TSHR
SCHEMBL5985439 0.77 DNM1 (0.48) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL24103978 0.77 DNM1 (0.67) DNM1S1PR2S1PR1S1PR3S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1694858-B1 METHOD FOR DETECTING PATHOGENIC MYCOBACTERIA IN CLINICAL SPECIMENS COUNCIL SCIENT IND RES (IN) 2009-06-17 EP claimed
US-20230272439-A1 METHOD FOR PRODUCING OLIVETOLIC ACID IN AN AMOEBOZOA HOST SPECIES LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E. V. HANS-KNÖLL-INSTITUT (HKI) (DE) 2023-08-31 US disclosed
EP-4176054-A1 METHOD FOR PRODUCING OLIVETOLIC ACID IN AN AMOEBOZOA HOST SPECIES Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. -Hans-Knöll-Institut- (HKI) (DE) 2023-05-10 EP disclosed
EP-4028009-A1 TREATMENT OF HR DEFICIENT CANCER The Francis Crick Institute Limited (GB) 2022-07-20 EP disclosed
WO-2022003126-A1 METHOD FOR PRODUCING OLIVETOLIC ACID IN AN AMOEBOZOA HOST SPECIES LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E. V. HANS-KNÖLL-INSTITUT (HKI) (DE) 2022-01-06 WO disclosed
WO-2021048235-A1 TREATMENT OF HR DEFICIENT CANCER THE FRANCIS CRICK INSTITUTE LIMITED (GB) 2021-03-18 WO disclosed
EP-3215496-B1 PANTOTHENAMIDE ANALOGUES RADBOUD UNIV MEDISCH CENTRUM (NL) 2019-01-02 EP disclosed
EP-3287126-A1 METHODS OF USING SNS-595 FOR TREATMENT OF CANCER SUBJECTS WITH REDUCED BRCA2 ACTIVITY Sunesis Pharmaceuticals, Inc. (US) 2018-02-28 EP disclosed
EP-3215496-A2 PANTOTHENAMIDE ANALOGUES Radboud Universitair Medisch Centrum (NL) 2017-09-13 EP disclosed
US-20170182015-A1 METHODS OF USING SNS-595 FOR TREATMENT OF CANCER SUBJECTS WITH REDUCED BRCA2 ACTIVITY SUNESIS PHARMACEUTICALS INC (US) 2017-06-29 US disclosed
US-6211336-B1 AMINO ACID SEQUENCE USED IN THE DIAGNOSIS AND TREATMENT OF NERVOUS SYSTEM GENETIC DISORDER; FOR CANCER SCREENING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2001-04-03 US disclosed
US-6200749-B1 AJUSTED NUCLEIC ACID SEQUENCE; FOR DETECTION OF GENOME ADJUSTMENTS AND PREFERENTIAL GENETIC DISORDERS RAMOT-UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) 2001-03-13 US disclosed
EP-1073748-A2 VACCINES CONTAINING RECOMBINANT PILIN AGAINST NEISSERIA GONORRHOEAE OR NEISSERIA MENINGITIDIS AMERICAN CYANAMID COMPANY (US) 2001-02-07 EP disclosed
EP-0826033-A4 ATAXIA-TELANGIECTASIA GENE UNIV RAMOT (IL) 2000-09-06 EP disclosed
EP-0826031-A4 ATAXIA-TELANGIECTASIA GENE AND ITS GENOMIC ORGANIZATION UNIV RAMOT (IL) 2000-09-06 EP disclosed
WO-1999055875-A2 VACCINES CONTAINING RECOMBINANT PILIN AGAINST NEISSERIA GONORRHOEAE OR $i(NEISSERIA MENINGITIDIS) AMERICAN CYANAMID COMPANY (US) 1999-11-04 WO disclosed
EP-0826033-A1 ATAXIA-TELANGIECTASIA GENE RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) 1998-03-04 EP disclosed
EP-0826031-A1 ATAXIA-TELANGIECTASIA GENE AND ITS GENOMIC ORGANIZATION RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) 1998-03-04 EP disclosed
WO-1996036695-A1 ATAXIA-TELANGIECTASIA GENE RAMOT-UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT, LTD. (IL) 1996-11-21 WO disclosed
WO-1996036691-A1 ATAXIA-TELANGIECTASIA GENE AND ITS GENOMIC ORGANIZATION RAMOT-UNIV. AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) 1996-11-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170182015-A1 METHODS OF USING SNS-595 FOR TREATMENT OF CANCER SUBJECTS WITH REDUCED BRCA2 ACTIVITY BRCA1, MRE11, RAD51 DNM1 2503/4885S1PR2 1118/4885S1PR1 946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.