Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611885 | 0.95 | DNM1 (0.44) | DNM1KCNH2TSHRTHRBKDM5A | |
| SCHEMBL15720779 | 0.95 | DNM1 (0.44) | DNM1KCNH2TSHRTHRBKDM5A | |
| SCHEMBL1461490 | 0.95 | DNM1 (0.44) | DNM1KCNH2TSHRTHRBKDM5A | |
| SCHEMBL1461504 | 0.93 | DNM1 (0.40) | DNM1KCNH2TSHRKDM5APHF8 | |
| SCHEMBL1462537 | 0.85 | CA12 (0.39) | KCNH2KDM5APHF8KDM4C | |
| SCHEMBL1461480 | 0.79 | DNM1 (0.48) | DNM1TSHRTHRBKDM5APHF8 | |
| SCHEMBL184235 | 0.79 | DNM1 (0.48) | DNM1TSHRTHRBKDM5APHF8 | |
| SCHEMBL24372535 | 0.76 | DNM1 (0.55) | DNM1KCNH2TSHRTHRBKDM5A | |
| SCHEMBL24728617 | 0.76 | DNM1 (0.55) | DNM1KCNH2TSHRTHRBKDM5A | |
| SCHEMBL24113636 | 0.76 | DNM1 (0.55) | DNM1KCNH2TSHRTHRBKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5186940-A | Antitumor agents | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1993-02-16 | — | — | US | disclosed |
| US-5178876-A | Antitumor agents | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1993-01-12 | — | — | US | disclosed |
| US-5041581-A | Antitumor agents | THE UNIVERSITY OF TEXAS SYSTEM BOARD OF REGENTS (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0248036-A1 | HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES. | UNIV TEXAS (US) | 1987-12-09 | — | — | EP | disclosed |
| WO-1987002364-A1 | HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1987-04-23 | — | — | WO | disclosed |