Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204374 | 0.85 | DPP4 (0.34) | DPP4DPP8DPP9GLRA1F2R | |
| SCHEMBL9976646 | 0.79 | GLRA1 (0.37) | RIPK1DPP4DPP8DPP9GLRA1 | |
| SCHEMBL17149733 | 0.78 | DPP4 (0.38) | DPP4DPP8DPP9GLRA1CNR2 | |
| Hydrochloric Acid SCHEMBL17142082 | 0.77 | DPP4 (0.37) | DPP4DPP8DPP9GLRA1 | |
| SCHEMBL20920355 | 0.76 | RIPK1 (0.37) | RIPK1NAMPT | |
| SCHEMBL12335245 | 0.76 | RIPK1 (0.42) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL12334716 | 0.73 | GNAI3 (0.46) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL17142081 | 0.73 | CNR2 (0.41) | DPP4DPP8DPP9CNR2 | |
| SCHEMBL12335246 | 0.72 | RIPK1 (0.54) | RIPK1 | |
| SCHEMBL20792933 | 0.72 | RIPK1 (0.54) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9555041-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2017-01-31 | — | — | US | disclosed |