Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12363731 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL23870872 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL12986052 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL26784870 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL23871038 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL25475327 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL12985917 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL23803397 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL9244959 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDATML3MBTL1 | |
| SCHEMBL795218 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9555041-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2017-01-31 | — | — | US | disclosed |