Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 15/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20273063 | 0.80 | CA1 (0.41) | MMP8CA1CA2CA7CTSL | |
| SCHEMBL28992920 | 0.79 | AAK1 (0.33) | MMP8AAK1POLBCA1CA2 | |
| SCHEMBL22001990 | 0.79 | GAA (0.33) | POLB | |
| SCHEMBL27433822 | 0.78 | EPHX1 (0.33) | PIK3CD | |
| SCHEMBL7819855 | 0.77 | ALDH1A1 (0.35) | POLBCA1CA7CTSK | |
| SCHEMBL609954 | 0.76 | MMP8 (0.37) | MMP8CA1CA2CA7PIK3CD | |
| SCHEMBL14586294 | 0.75 | TDP1 (0.32) | — | |
| SCHEMBL18680190 | 0.75 | POLB (0.32) | POLB | |
| SCHEMBL27623170 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL12869155 | 0.74 | GAA (0.43) | MMP8AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556167-B2 | TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs) | YALE UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |