Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429639 | 0.84 | APP (0.70) | APPRXRARXRB | |
| SCHEMBL1259197 | 0.83 | NPC1 (0.55) | APPNPC1ALDH1A1RAB9A | |
| SCHEMBL940824 | 0.82 | P4HTM (0.58) | NPC1ALDH1A1RAB9A | |
| SCHEMBL18429796 | 0.79 | APP (0.64) | APPRXRARXRB | |
| SCHEMBL6802570 | 0.79 | P4HTM (0.55) | NPC1ALDH1A1RAB9A | |
| SCHEMBL18429785 | 0.79 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL27987961 | 0.78 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL18429760 | 0.78 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL16389670 | 0.77 | APP (0.60) | APP | |
| SCHEMBL6551669 | 0.76 | LMNA (0.59) | NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581565-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | Beijing Zhibo Bio-Medical Technology Co., Ltd. (CN) | 2019-12-18 | — | — | EP | disclosed |
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | ZHANG ZHIYONG (CN) | 2017-02-09 | — | — | US | disclosed |
| CN-103724207-B | Phenylbenzyl ether derivative and its preparation method and application | 北京智博高科生物技术有限公司 | 2016-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | APP, PSEN1, PSEN2 | APP 1/4885RXRA 482/4885RXRB 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.