Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113864 | 0.76 | ULK1 (0.33) | — | |
| SCHEMBL31716510 | 0.75 | NOS2 (0.41) | GAAMAPK1POLB | |
| SCHEMBL11568803 | 0.72 | NPSR1 (0.41) | NPSR1L3MBTL1GAAMAPK1POLB | |
| SCHEMBL885349 | 0.70 | DRD1 (0.42) | L3MBTL1GAAPOLB | |
| SCHEMBL15579764 | 0.69 | NPSR1 (0.40) | NPSR1L3MBTL1GAAMAPK1POLB | |
| SCHEMBL7715366 | 0.69 | NPSR1 (0.43) | NPSR1L3MBTL1GAAMAPK1POLB | |
| SCHEMBL15579767 | 0.69 | NPSR1 (0.40) | NPSR1L3MBTL1GAAMAPK1POLB | |
| SCHEMBL11005476 | 0.69 | IDO1 (0.46) | NPSR1L3MBTL1GAAMAPK1 | |
| SCHEMBL12199974 | 0.69 | NPSR1 (0.43) | NPSR1L3MBTL1GAAMAPK1POLB | |
| SCHEMBL12199965 | 0.69 | NPSR1 (0.43) | NPSR1L3MBTL1GAAMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320732-A2 | SUBSTITUTED IMIDAZOLE COMBINATIONS | Pfizer Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010020896-A2 | SUBSTITUTED IMIDAZOLE COMBINATIONS | PFIZER INC. (US) | 2010-02-25 | — | — | WO | disclosed |