Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840520 | 0.88 | CALCRL (0.47) | CALCRLCYP3A4HSD11B1CHRM2CHRM4 | |
| SCHEMBL1832814 | 0.84 | CHRM2 (0.53) | CALCRLCYP3A4CCR5HSD11B1CHRM2 | |
| SCHEMBL1834519 | 0.84 | CHRM2 (0.53) | CALCRLCYP3A4CCR5HSD11B1CHRM2 | |
| SCHEMBL1834521 | 0.84 | CHRM2 (0.53) | CALCRLCYP3A4CCR5HSD11B1CHRM2 | |
| SCHEMBL1838916 | 0.82 | OPRM1 (0.44) | CCR5HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL3805980 | 0.81 | OPRM1 (0.46) | CALCRLHSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL3804652 | 0.79 | CALCRL (0.49) | CALCRLCYP3A4HSD11B1CHRM2CHRM4 | |
| SCHEMBL1838918 | 0.79 | OPRM1 (0.44) | CCR5HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL4677810 | 0.78 | OPRM1 (0.50) | CALCRLHSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL4677814 | 0.78 | OPRM1 (0.50) | CALCRLHSD11B1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-2160098-B1 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-11-10 | — | — | EP | claimed |