Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | PLD2 | O14939 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840520 | 0.85 | CALCRL (0.47) | CALCRLCYP3A4OPRM1OPRK1OPRL1 | |
| SCHEMBL3805980 | 0.81 | OPRM1 (0.46) | CALCRLOPRM1OPRK1OPRL1HSD11B1 | |
| SCHEMBL1833614 | 0.81 | CHRM2 (0.59) | CALCRLCYP3A4OPRM1OPRK1OPRL1 | |
| SCHEMBL1833607 | 0.81 | CHRM2 (0.59) | CALCRLCYP3A4OPRM1OPRK1OPRL1 | |
| SCHEMBL1833610 | 0.81 | CHRM2 (0.59) | CALCRLCYP3A4OPRM1OPRK1OPRL1 | |
| SCHEMBL1843369 | 0.79 | CALCRL (0.42) | CALCRLCYP3A4OPRM1OPRK1OPRL1 | |
| SCHEMBL4677810 | 0.79 | OPRM1 (0.50) | CALCRLOPRM1OPRK1OPRL1HSD11B1 | |
| SCHEMBL4677814 | 0.79 | OPRM1 (0.50) | CALCRLOPRM1OPRK1OPRL1HSD11B1 | |
| SCHEMBL1837269 | 0.77 | OPRM1 (0.54) | CYP3A4OPRM1OPRK1OPRL1HSD11B1 | |
| SCHEMBL27782364 | 0.77 | OPRM1 (0.58) | OPRM1OPRK1OPRL1HSD11B1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-A2 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | Commissariat a L'Energie Atomique (FR) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008146174-A2 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |