Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066582 | 0.97 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL939704 | 0.97 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL5183148 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| Water SCHEMBL28268738 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| Hydrochloric Acid SCHEMBL3809505 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| Hydrochloric Acid SCHEMBL28717387 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL3706280 | 0.88 | HPRT1 (0.64) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL15655937 | 0.84 | CYP2A6 (0.58) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL1925928 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL28471772 | 0.84 | CYP1A2 (0.41) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626052-B1 | PROCESS FOR PRODUCTION OF PHOSPHINE-BORANE COMPLEXES | TAKEDA PHARMACEUTICAL (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-7541498-B2 | Process for production of phosphine-borane complexes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| CN-100412079-C | Process for production of phosphine-borane complexes | TAKEDA PHARMACEUTICAL (JP) | 2008-08-20 | — | — | CN | disclosed |
| US-20060199968-A1 | Process for production of phosphine-borane complexes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| CN-1788011-A | Process for production of phosphine-borane complexes | TAKEDA PHARMACEUTICAL (JP) | 2006-06-14 | — | — | CN | disclosed |
| EP-1626052-A1 | PROCESS FOR PRODUCTION OF PHOSPHINE-BORANE COMPLEXES | Takeda Pharmaceutical Company Limited (JP) | 2006-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199968-A1 | Process for production of phosphine-borane complexes | BRS3, BRPF1, BRSK1 | ALDH1A1 4513/4885HSD17B10 2502/4885TSHR 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.