Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.66 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973343 | 0.80 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434829 | 0.72 | SLC40A1 (0.57) | SLC40A1 | |
| SCHEMBL18434446 | 0.72 | SLC40A1 (0.57) | SLC40A1 | |
| SCHEMBL11973036 | 0.72 | LMNA (0.43) | SLC40A1 | |
| SCHEMBL4208987 | 0.71 | CHRNA7 (0.52) | SLC40A1CDK1CDK2ABL1AR | |
| SCHEMBL11973758 | 0.71 | SLC40A1 (0.61) | SLC40A1 | |
| SCHEMBL18434560 | 0.70 | KDM4E (0.41) | SLC40A1 | |
| SCHEMBL11973491 | 0.70 | SLC40A1 (0.49) | SLC40A1 | |
| SCHEMBL18434437 | 0.70 | SLC40A1 (0.52) | SLC40A1 | |
| SCHEMBL11973407 | 0.70 | SLC40A1 (0.62) | SLC40A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |