Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16285217 | 0.78 | SLC40A1 (0.58) | SLC40A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL18434454 | 0.76 | SLC40A1 (0.53) | SLC40A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL16285219 | 0.75 | SLC40A1 (0.62) | SLC40A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL16285218 | 0.75 | SLC40A1 (0.45) | SLC40A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL11973742 | 0.75 | SLC40A1 (0.60) | SLC40A1MEN1KMT2AGLO1KDM4E | |
| SCHEMBL18434687 | 0.73 | SLC40A1 (0.48) | SLC40A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL11995664 | 0.72 | SLC40A1 (1.00) | SLC40A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL1994732 | 0.65 | CCR1 (0.57) | SLC40A1MEN1KMT2AGLO1KDM4E | |
| SCHEMBL30492680 | 0.65 | CCR1 (0.57) | SLC40A1MEN1KMT2AGLO1KDM4E | |
| SCHEMBL5094221 | 0.64 | MMP2 (0.47) | SLC40A1MEN1KMT2AGLO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |