Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | CKS1B | P61024 | 2/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434725 | 0.78 | SLC40A1 (0.57) | SLC40A1KDM4EMEN1KMT2APAX8 | |
| SCHEMBL11995662 | 0.77 | SLC40A1 (1.00) | SLC40A1MEN1KMT2ACKS1BSKP2 | |
| SCHEMBL18434572 | 0.74 | SLC40A1 (0.56) | SLC40A1RPS6KB1KDM4EMEN1TNF | |
| SCHEMBL29800755 | 0.66 | SLC40A1 (0.69) | SLC40A1MEN1KMT2ACKS1BSKP2 | |
| SCHEMBL26964128 | 0.66 | SLC40A1 (0.69) | SLC40A1MEN1KMT2ACKS1BSKP2 | |
| SCHEMBL18205912 | 0.65 | SLC40A1 (0.61) | SLC40A1RPS6KB1KDM4EKMT2ATRPV1 | |
| SCHEMBL28589637 | 0.62 | PTPRZ1 (0.40) | SLC40A1CHEK1KDM4EMEN1KMT2A | |
| SCHEMBL21148901 | 0.62 | SLC40A1 (0.54) | SLC40A1RPS6KB1KDM4EMEN1KMT2A | |
| SCHEMBL21869662 | 0.62 | CKS1B (0.60) | CKS1BSKP2 | |
| SCHEMBL21869714 | 0.62 | CKS1B (0.65) | CKS1BSKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |