Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434720 | 0.78 | SLC40A1 (0.62) | SLC40A1KDM4EMEN1KMT2APAX8 | |
| SCHEMBL11973112 | 0.72 | SLC40A1 (0.58) | SLC40A1GLO1HTTALOX15CYP3A4 | |
| SCHEMBL11973714 | 0.72 | SLC40A1 (1.00) | SLC40A1GLO1HTTTDP1MAPT | |
| SCHEMBL1996991 | 0.69 | CCR1 (0.61) | SLC40A1GLO1HTTALOX15CYP3A4 | |
| SCHEMBL7704782 | 0.68 | GLO1 (0.51) | SLC40A1GLO1HTTALOX15CYP3A4 | |
| SCHEMBL17749155 | 0.65 | GLO1 (0.56) | SLC40A1GLO1HTTALOX15CYP3A4 | |
| SCHEMBL2481131 | 0.65 | CYP3A4 (0.61) | SLC40A1GLO1HTTALOX15CYP3A4 | |
| SCHEMBL31130165 | 0.65 | CYP3A4 (0.61) | SLC40A1GLO1HTTALOX15CYP3A4 | |
| SCHEMBL379216 | 0.65 | GLO1 (0.59) | SLC40A1GLO1HTTALOX15CYP3A4 | |
| Hydrochloric Acid SCHEMBL28066152 | 0.64 | CYP3A4 (0.59) | SLC40A1GLO1HTTALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |