Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973017 | 0.79 | MEN1 (0.48) | GAAKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL11973767 | 0.70 | KMT2A (0.56) | GAAKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL11973822 | 0.67 | SLC40A1 (0.64) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL24715769 | 0.67 | MAPT (0.52) | GAAKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL11972993 | 0.66 | SLC40A1 (0.47) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL11973471 | 0.65 | SLC40A1 (0.53) | ALDH1A1SLC40A1NFKBIARELA | |
| SCHEMBL11973375 | 0.63 | DYRK1A (0.45) | NPC1SLC40A1 | |
| SCHEMBL6537951 | 0.63 | KMT2A (0.51) | GAAKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL25247464 | 0.63 | KMT2A (0.49) | GAAKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL2469901 | 0.63 | ALDH1A1 (0.61) | GAAKMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |