Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406261 | 0.78 | — | — | |
| SCHEMBL25039323 | 0.76 | HTR2A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL19012529 | 0.74 | — | — | |
| SCHEMBL19001055 | 0.72 | ATM (0.33) | — | |
| SCHEMBL22113135 | 0.72 | OPRM1 (0.32) | — | |
| SCHEMBL22113128 | 0.71 | — | — | |
| SCHEMBL3089462 | 0.69 | FUCA1 (0.33) | FUCA1HTR2C | |
| SCHEMBL3590322 | 0.69 | FUCA1 (0.33) | FUCA1HTR2C | |
| SCHEMBL18569094 | 0.69 | FUCA1 (0.33) | FUCA1HTR2C | |
| SCHEMBL18580080 | 0.68 | GBA1 (0.37) | GBA1FUCA1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-B1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO LTD (CN) | 2019-09-11 | — | — | EP | disclosed |
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |