Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308792 | 0.94 | HPRT1 (0.38) | RXRARARATDP1RARBRARG | |
| SCHEMBL18308781 | 0.94 | HPRT1 (0.38) | RXRARARATDP1RARBRARG | |
| SCHEMBL18308780 | 0.87 | RXRA (0.31) | RXRARARAMAPK14 | |
| SCHEMBL18308784 | 0.87 | RXRA (0.31) | RXRARARAMAPK14 | |
| SCHEMBL15435579 | 0.84 | ESRRA (0.41) | ALDH1A1TDP1MAPT | |
| SCHEMBL18308798 | 0.83 | MAPK14 (0.30) | MAPK14 | |
| SCHEMBL18308742 | 0.82 | ESR2 (0.41) | ALDH1A1CYP3A4TSHRTDP1RARB | |
| SCHEMBL18806017 | 0.82 | — | — | |
| SCHEMBL18308760 | 0.81 | MCL1 (0.42) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL18308739 | 0.81 | MCL1 (0.42) | ALDH1A1CYP3A4TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124465-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-02-01 | — | — | EP | disclosed |