Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308786 | 0.94 | ESR2 (0.37) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308763 | 0.94 | ESR2 (0.37) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308754 | 0.91 | ESR2 (0.41) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308767 | 0.90 | ESR2 (0.39) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308740 | 0.88 | ESR2 (0.42) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308753 | 0.88 | ESR2 (0.38) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308762 | 0.87 | RARB (0.35) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308748 | 0.87 | RARB (0.35) | ESR2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18308787 | 0.87 | ESR2 (0.40) | ESR2ALDH1A1TDP1HSD17B1ESR1 | |
| SCHEMBL18308749 | 0.86 | ESR2 (0.43) | ESR2ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-20230183571-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-06-15 | — | — | US | disclosed |
| EP-3275973-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2019-12-18 | — | — | EP | disclosed |
| US-20180201837-A1 | Method of Reducing ODF Mura in Polymer Stabilised Liquid Crystal Displays | MERCK PATENT GMBH (DE) | 2018-07-19 | — | — | US | disclosed |
| EP-3275973-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | GMBH, MERCK PATENT (DE) | 2017-05-04 | — | — | US | disclosed |
| EP-3121247-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2017008884-A1 | METHOD OF REDUCING ODF MURA IN POLYMER STABILISED LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | WO | disclosed |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | ESR2 4146/4885ALDH1A1 4572/4885CYP3A4 1699/4885 |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LCP1, MAP1LC3C | ESR2 4322/4885ALDH1A1 4590/4885CYP3A4 2477/4885 |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | ESR2 4381/4885ALDH1A1 4429/4885CYP3A4 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.